Symbiotic treatment in hospitalized patients: impact on constipation

Authors

  • Sandramara Sasso
  • Fabiane LaFlor Ziegler Sanches
  • Rosângela dos Santos Ferreira
  • Rita de Cássia Avellaneda Guimarães Universidade Federal de Mato Grosso do Sul (UFMS)

DOI:

https://doi.org/10.20435/1119

Keywords:

constipation, prebiotics, probiotics.

Abstract

The aim of this study was to evaluate the effect of symbiotic treatment on intestinal function in constipated hospitalized patients. The study where with 24 constipated patients of both sexes in a hospital environment were randomized into two groups to receive maltodextrin (control group) and symbiotic treatment (experimental group) daily for 7 days. In relation to defecation frequency, there was no statistical difference between the groups. The percentage of patients who had no evacuation report in the experimental group decreased on days 1 (66.7%), 4 (41.7%) and 7 (33.3%), while the control group did not show such effect. It was found that symbiotic treatment did not lead to an increase in abdominal symptoms in either the experimental or placebo group. The present study showed that symbiotic treatment for 7 days is insufficient to achieve significant results, especially in defecation frequency and stool consistency and shape.

Author Biographies

Sandramara Sasso

Mestre. Universidade Federal de Mato Grosso do Sul. Programa de Residência Multiprofissional: Atenção ao Paciente Crítico/ PREMUS/UFMS. CEP: 79900-000, Campo Grande, MS, Brasil E-mail: sandramara_sasso@hotmail.com

Fabiane LaFlor Ziegler Sanches

Doutora. Universidade Federal de Mato Grosso do Sul. CEP: 79900-000, Campo Grande, MS, Brasil. E-mail: fabianelaflor@gmail.com

Rosângela dos Santos Ferreira

Doutora. Universidade Federal de Mato Grosso do Sul. CEP: 79900-000, Campo Grande, MS, Brasil. E-mail: fabianelaflor@gmail.com

Rita de Cássia Avellaneda Guimarães, Universidade Federal de Mato Grosso do Sul (UFMS)

Doutora. Programa de Pós Graduação em Saúde e Desenvolvimento na Região Centro-Oeste. Faculdade de Medicina. Universidade Federal de Mato Grosso do Sul. CEP: 79900-000, Campo Grande, MS, Brasil. E-mail: rita.guimaraes@ufms.com

References

FATEHA, R.; IRAVANIB, S.; FROOTANC, M.; RASOULID, M. R.; SAADATD, S. Synbiotic preparation in men suffering from functional constipation: a randomised controlled trial. Swiss Medical Weekly, Tehran, v. 30, 2011.

GACOUIN, A.; CAMUS, C.; GROS, A.; ISSLAME, S.; MARQUE, S.; LAVOUÉ, S.; CHIMOT, L.; DONNIO, P.; TULZO, Y. L. Constipation in long-term ventilated patients: associated factors and impact on intensive care unit outcomes. Critical Care Medicine, Rennes, v. 38, n. 10, p. 1933-1938, 2010.

GUARNER, F.; KHAN, A. G.; GARISCH, J.; ELIAKIM; R.; GANGL, A.; THOMSON, A.; KRABSHUIS, J.; LEMAIR, T. World Gastroenterology Organisation Global Guidelines: Probiotics and prebiotics. 2011. Available at: http://www.worldgastroenterology.org/assets/export/userfiles/Probiotics_FINAL_20110116.pdf>. Accessed 4 January 2015

GUERRA, T. L. S.; MENDONCA, S. S.; MARSHALL, N. G. Incidência de constipação intestinal em uma unidade de terapia intensiva. Revista Brasileira de Terapia Intensiva, Brasília, v. 25, n. 2, p. 87-92, 2013b.

LEWIS, S. J.; HEATON, K. W. Stool form scale as a useful guide to intestinal transit time scand. Journal of Gastroenterology, London, v. 32, n. 9, p. 920-924, 2007.

LIU, Z.; XU, Z.; HAN, M.; GUO, B. Efficacy of pasteurised yoghurt in improving chronic constipation: A randomised, double-blind, placebo-controlled trial. International Dairy Journal, Shanghai, v. 40, p. 1-5, 2015.

LOPES, A. C.; VICTORIA, C. R. Ingestão de fibra alimentar e tempo de trânsito colônico em pacientes com constipação funcional. Arquivo de Gastroenterologia, Botucatu, SP, v. 45, n. 1, p. 58-63, 2008.

MALAGUARNERA, M.; VACANTE, M.; CONDORELLI, G.; LEGGIO, F.; ROSA, M.; MOTTA, M.; MALAGUARNERA, G.; ALESSANDRIA, I.; RAMPELLO, L.; CHISARI, G. Probiotics and prebiotics in the management of constipation in the elderly. Best Practice & Research Clinical Gastroenterology, Columbus, v. 25, n. 1, p. 3-18, 2013.

MOSTAFA, S.M.; BHANDARI, S.; RITCHIE, G.; GRATTON, N.; WENSTONE, R. Constipation and its implications in the critically ill patient. British Journal of Anaesthesia, Liverpool, v. 91, n. 6, p. 815-819, 2003.

MUGIE, S. M.; BENNINGA, M. A.; DI LORENZO, C. Epidemiology of constipation in children and adults: A systematic review. Best Practice & Research Clinical Gastroenterology, v. 25, p. 3-18, 2011.

NASSAR, A. P. JR.; SILVA, F. M. Q.; CLEVA, R. Constipation in intensive care unit: Incidence and risk factors. Journal of Critical Care, São Paulo, v. 24, n. 4, p. 630-639, 2009.

PATANWALA, A. E.; ABARCA, J.; HUCKLEBERRY, Y.; ERSTAD, B.L.; Pharmacologic management of constipation in the critically ill patient. Pharmacotherapy, Arizona, v. 26, n. 7, p. 896-902, 2006.

RAIZEL, R.; SANTINI, E.; KOPPER, A. M.; FILHO, A. D. R. Efeitos do consumo de probióticos, prebióticos e simbióticos para o organismo humano. Revista Ciência & Saúde, Porto Alegre, v. 4, n. 2, p. 66-74, 2011.

VAN DER SPOEL, J. I.; SCHULTZ, M. J.; VAN DER VOORT, P.H.; JONGE, E. Influence of severity of illness, medication and selective decontamination on defecation. Intensive Care Medicine, Amsterdam, v. 32, n. 6, p. 875-80, 2006.

WAITZBERG, D. L.; LOGULLO, L. C.; BITTENCOURT, A. F.; TORRINHAS, R. S.; SHIROMA, G. M.; PAULINO, N.P., TEIXEIRA-DA-SILVA ML. Effect of symbiotic in constipated adult women - a randomized, double-blind, placebo-controlled study of clinical response. Clinical Nutrition, São Paulo, v. 32, n. 1, p. 27-33, 2013.

Published

2016-11-17

How to Cite

Sasso, S., Sanches, F. L. Z., Ferreira, R. dos S., & Guimarães, R. de C. A. (2016). Symbiotic treatment in hospitalized patients: impact on constipation. Multitemas, 21(50). https://doi.org/10.20435/1119